BindingDB BDBM50028962 CHEMBL275638::flavone

BDBM50028962 CHEMBL275638::flavone

SMILES O=c1cc(oc2ccccc12)-c1ccccc1

InChI Key InChIKey=VHBFFQKBGNRLFZ-UHFFFAOYSA-N

Data 18 KI 18 IC50 1 Kd

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50028962

Amine oxidase [flavin-containing] A(Homo sapiens (Human))
Birla Institute of Technology

BDBM50028962(CHEMBL275638 | flavone)

Ki: 2.50E+3nMAssay Description:The activities of recombinant hMAO-A and hMAO-B were determined using p-tyramine as common substrate and calculated as 0.18 +/- 0.01 nmol/mg/min (n =...More data for this Ligand-Target Pair

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Filter my 37 hits

Targets 24▿
- Adenosine receptor A1 3
- Adenosine receptor A3 3
- Aromatase 3
- Carbonic anhydrase 12 2
- Carbonic anhydrase 1 2
- Androgen receptor 2
- Broad substrate specificity ATP-binding cassette transporter ABCG2 2
- Carbonic anhydrase 9 2
- Carbonic anhydrase 2 2
- Adenosine receptor A2a 2
- Amine oxidase [flavin-containing] B 1
- Amine oxidase [flavin-containing] A 1
- Poly [ADP-ribose] polymerase tankyrase-1 1
- DNA-dependent protein kinase catalytic subunit 1
- Poly [ADP-ribose] polymerase tankyrase-2 1
- Epidermal growth factor receptor 1
- ATP-dependent translocase ABCB1 1
- Cytochrome P450 1B1 1
- Dihydroorotate dehydrogenase (quinone), mitochondrial 1
- Dipeptidyl peptidase 4 1
- Dipeptidyl peptidase 3 1
- Calmodulin-1 1
- Dihydroorotate dehydrogenase (fumarate) 1
- Poly [ADP-ribose] polymerase 1 1
Publications 20▿
- Bioorg Med Chem Lett 22: 3063-6 (2012) 8
- J Med Chem 56: 3507-17 (2013) 3
- J Med Chem 41: 46-52 (1998) 3
- J Med Chem 39: 781-8 (1996) 3
- Bioorg Med Chem 19: 2090-102 (2011) 2
- Bioorg Med Chem Lett 19: 972-5 (2009) 2
- Bioorg Chem 58: 72-80 (2015) 2
- J Med Chem 39: 2293-301 (1996) 2
- Chem Biol Drug Des 89: 619-627 (2017) 1
- Eur J Med Chem 135: 296-306 (2017) 1
- J Med Chem 48: 569-85 (2005) 1
- Bioorg Med Chem 22: 126-34 (2013) 1
- J Med Chem 48: 5666-74 (2005) 1
- Eur J Med Chem 46: 4078-88 (2011) 1
- Eur J Med Chem 102: 375-86 (2015) 1
- J Nat Prod 55: 1529-1560 (1992) 1
- Bioorg Med Chem 19: 542-6 (2011) 1
- Bioorg Med Chem Lett 19: 4706-10 (2009) 1
- Bioorg Med Chem Lett 20: 3050-64 (2010) 1
- Eur J Med Chem 151: 145-157 (2018) 1
Institutions 17▿
- Universit£ 9
- National Institute Of Diabetes 8
- University Of Oulu 3
- Birla Institute of Technology 2
- Harvard School Of Public Health 2
- University Of Bonn 2
- Northern Kentucky University 1
- TBA 1
- Johns Hopkins University 1
- University Of Basel 1
- Chosun University 1
- Chinese Academy Of Sciences 1
- Meijo University 1
- Newcastle University 1
- American University Of Ras Al Khaimah 1
- Josip Juraj Strossmayer University of Osijek 1
- Universidad Aut£Noma Del Estado De Morelos 1
Affinity: 8 to 2.9E+5 nM▿
- Ki 18
- IC50 18
- Kd 1
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 1